PF-543

Catalog No. A13039

PF-543是一种新型选择性SK-1抑制剂,可与鞘氨醇竞争性抑制SK-1活性。
Catalog Num A13039
M. Wt 465.6
Formula C27H31NO4S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1415562-82-1
Synonyms PF543,PF 543
SMILES CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCC[C@@H]3CO)CS(=O)(=O)C4=CC=CC=C4
PF-543是一种新型选择性SK-1抑制剂,可与鞘氨醇竞争性抑制SK-1活性。
Targets
SphK1 SphK1
2.0 nM3.6 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.48 mL 107.39 mL 214.78 mL
0.5 mM 4.3 mL 21.48 mL 42.96 mL
1 mM 2.15 mL 10.74 mL 21.48 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.