PF-543
Catalog No. A13039
PF-543是一种新型选择性SK-1抑制剂,可与鞘氨醇竞争性抑制SK-1活性。
Catalog Num | A13039 |
---|---|
M. Wt | 465.6 |
Formula | C27H31NO4S |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1415562-82-1 |
Synonyms | PF543,PF 543 |
SMILES | CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCC[C@@H]3CO)CS(=O)(=O)C4=CC=CC=C4 |
PF-543是一种新型选择性SK-1抑制剂,可与鞘氨醇竞争性抑制SK-1活性。
Targets
SphK1 | SphK1 | |||
2.0 nM | 3.6 nM(Ki) |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.48 mL | 107.39 mL | 214.78 mL |
0.5 mM | 4.3 mL | 21.48 mL | 42.96 mL |
1 mM | 2.15 mL | 10.74 mL | 21.48 mL |
5 mM | 0.43 mL | 2.15 mL | 4.3 mL |
*The above data is based on the productmolecular weight 465.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.