R1530
Catalog No. A13111
R1530是吡唑并苯并二氮杂小分子，具有潜在的抗血管生成和抗肿瘤活性。R1530也是一种有丝分裂-血管生成抑制剂(MAI),可抑制多种参与血管生成的受体酪氨酸激酶，如血管内皮生长因子受体(VEGFR)-1，-2，-3，血小板衍生生长因子受体(PDGFR)βFMS样酪氨酸激酶(Flt)-3和成纤维细胞生长因子受体(FGFR) -1，-2。
| Catalog Num | A13111 |
|---|---|
| M. Wt | 356.78 |
| Formula | C18H14ClFN4O |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 882531-87-5 |
| Synonyms | R-1530, R 1530 |
| SMILES | CC1=C2C(=NC3=CC(=C(C=C3C(=N2)C4=CC=CC=C4Cl)F)OC)NN1 |
R1530是吡唑并苯并二氮杂小分子，具有潜在的抗血管生成和抗肿瘤活性。R1530也是一种有丝分裂-血管生成抑制剂(MAI),可抑制多种参与血管生成的受体酪氨酸激酶，如血管内皮生长因子受体(VEGFR)-1，-2，-3，血小板衍生生长因子受体(PDGFR)βFMS样酪氨酸激酶(Flt)-3和成纤维细胞生长因子受体(FGFR) -1，-2。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.03 mL | 140.14 mL | 280.28 mL |
| 0.5 mM | 5.61 mL | 28.03 mL | 56.06 mL |
| 1 mM | 2.8 mL | 14.01 mL | 28.03 mL |
| 5 mM | 0.56 mL | 2.8 mL | 5.61 mL |
*The above data is based on the productmolecular weight 356.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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