RGB-286638
Catalog No. A13130
RGB-286638是一种新型CDK抑制剂，对于细胞周期蛋白T1-CDK9/细胞周期蛋白B1-CDK1/细胞周期蛋白E-CDK2/细胞周期蛋白D1-CDK4/细胞周期蛋白E-CDK3的IC50为1 nM/2 nM/3 nM/4 nM/5 nM/p35-CDK5分别；对细胞周期蛋白H-CDK7和细胞周期蛋白D3-CDK6的效力较低。
| Catalog Num | A13130 |
|---|---|
| M. Wt | 618.55 |
| Formula | C29H37Cl2N7O4 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 784210-87-3 |
| Synonyms | RGB286638, RGB 286638 |
| SMILES | COCCN1CCN(CC1)CC2=CC=C(C=C2)C3=NNC4=C3C(=O)C5=C4C=CC=C5NC(=O)NN6CCOCC6.Cl.Cl |
RGB-286638是一种新型CDK抑制剂，对于细胞周期蛋白T1-CDK9/细胞周期蛋白B1-CDK1/细胞周期蛋白E-CDK2/细胞周期蛋白D1-CDK4/细胞周期蛋白E-CDK3的IC50为1 nM/2 nM/3 nM/4 nM/5 nM/p35-CDK5分别；对细胞周期蛋白H-CDK7和细胞周期蛋白D3-CDK6的效力较低。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.17 mL | 80.83 mL | 161.67 mL |
| 0.5 mM | 3.23 mL | 16.17 mL | 32.33 mL |
| 1 mM | 1.62 mL | 8.08 mL | 16.17 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.23 mL |
*The above data is based on the productmolecular weight 618.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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