RG2833 (RGFP109)

Catalog No. A13139

RG2833 (RGFP109)是一种脑渗透性HDAC抑制剂,IC50为60 nM,HDAC1和HDAC3为50 nM。
Catalog Num A13139
M. Wt 339.43
Formula C20H25N3O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1215493-56-3
Synonyms RGFP109
SMILES CC1=CC=C(C=C1)C(=O)NCCCCCC(=O)NC2=CC=CC=C2N
RG2833 (RGFP109)是一种脑渗透性HDAC抑制剂,IC50为60 nM,HDAC1和HDAC3为50 nM。
Targets
HDAC3 (Cell-free assay) HDAC1 (Cell-free assay) HDAC3 (Cell-free assay) HDAC1 (Cell-free assay)
5 nM(Ki)32 nM(Ki)5 nM(Ki)32 nM(Ki)
In vitro DMSO 65 mg/mL (191.49 mM)
Water Insoluble
Ethanol 10 mg/mL (29.46 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.46 mL 147.31 mL 294.61 mL
0.5 mM 5.89 mL 29.46 mL 58.92 mL
1 mM 2.95 mL 14.73 mL 29.46 mL
5 mM 0.59 mL 2.95 mL 5.89 mL

*The above data is based on the productmolecular weight 339.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.