CNX-774

Catalog No. A13233

CNX-774是有效的Btk抑制剂（IC50 <1 nM）。

Technical details

Catalog Num	A13233
M. Wt	499.5
Formula	C26H22FN7O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1202759-32-7
Synonyms	CNX 774; CNX774
SMILES	CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC(=CC=C4)NC(=O)C=C)F

Biological Activity

CNX-774是有效的Btk抑制剂（IC50 <1 nM）。

Targets

BTK
<1 nM

Solubility *

In vitro	DMSO	89 mg/mL (178.18 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (4 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.02 mL	100.1 mL	200.2 mL
0.5 mM	4 mL	20.02 mL	40.04 mL
1 mM	2 mL	10.01 mL	20.02 mL
5 mM	0.4 mL	2 mL	4 mL

*The above data is based on the productmolecular weight 499.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.