Ferrostatin-1 (Fer-1)

Catalog No. A13247

Ferrostatin-1 (Fer-1)是一种有效的选择性铁锈病抑制剂，EC50为60 nM。

Product Citations

Xueyan Zhang, .et al. Dihydroartemisinin Triggers Ferroptosis in Multidrug-Resistant Leukemia Cells, DNA Cell Biol, 2022, Aug;41(8):705-715 PMID: 35687364
A Xavier, .et al. hGBP1 Coordinates Chlamydia Restriction and Inflammasome Activation Through Sequential GTP Hydrolysis, Cell Rep, 2020, May 19;31(7):107667 PMID: 32433976

Technical details

Catalog Num	A13247
M. Wt	262.35
Formula	C15H22N2O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	347174-05-4
Synonyms	Fer1
SMILES	CCOC(=O)C1=CC(=C(C=C1)NC2CCCCC2)N

Biological Activity

Ferrostatin-1 (Fer-1)是一种有效的选择性铁锈病抑制剂，EC50为60 nM。

Targets

Ferroptosis
60 nM(EC50)

Solubility *

In vitro (25°C)	DMSO	45 mg/mL (171.52 mM)
	Water	Insoluble
	Ethanol	45 mg/mL
In vivo	2% DMSO+50% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.12 mL	190.59 mL	381.17 mL
0.5 mM	7.62 mL	38.12 mL	76.23 mL
1 mM	3.81 mL	19.06 mL	38.12 mL
5 mM	0.76 mL	3.81 mL	7.62 mL

*The above data is based on the productmolecular weight 262.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.