E-64

Catalog No. A13257

E-64是一种不可逆的选择性半胱氨酸蛋白酶抑制剂，对木瓜蛋白酶的IC50为9 nM。

Technical details

Catalog Num	A13257
M. Wt	357.41
Formula	C15H27N5O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	66701-25-5
Synonyms	E64, E 64
SMILES	CC(C)C[C@@H](C(=O)NCCCCN=C(N)N)NC(=O)[C@@H]1[C@H](O1)C(=O)O

Biological Activity

E-64是一种不可逆的选择性半胱氨酸蛋白酶抑制剂，对木瓜蛋白酶的IC50为9 nM。

Targets

Cysteine protease
9 nM

Solubility *

In vitro	DMSO	Warmed: 61 mg/mL (170.67 mM)
	Water	Warmed: 9 mg/mL (25.18 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.98 mL	139.9 mL	279.79 mL
0.5 mM	5.6 mL	27.98 mL	55.96 mL
1 mM	2.8 mL	13.99 mL	27.98 mL
5 mM	0.56 mL	2.8 mL	5.6 mL

*The above data is based on the productmolecular weight 357.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.