PRX-08066
Catalog No. A13267
PRX-08066是一种新型的5-HT受体2B（5-HT2BR）拮抗剂，IC50为3.4 nM，，可减轻单芥子碱诱导的大鼠肺动脉高压和右室肥大。
| Catalog Num | A13267 |
|---|---|
| M. Wt | 401.89 |
| Formula | C19H17ClFN5S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 866206-54-4 |
| Synonyms | PRX08066, PRX 08066 |
| SMILES | C1CN(CCC1NC2=C3C=C(SC3=NC=N2)Cl)CC4=CC(=C(C=C4)F)C#N |
PRX-08066是一种新型的5-HT受体2B（5-HT2BR）拮抗剂，IC50为3.4 nM，，可减轻单芥子碱诱导的大鼠肺动脉高压和右室肥大。
| In vitro | DMSO | 92 mg/mL (177.61 mM) | |
| Water | 92 mg/mL (177.61 mM) | ||
| Ethanol | 86 mg/mL (166.03 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.88 mL | 124.41 mL | 248.82 mL |
| 0.5 mM | 4.98 mL | 24.88 mL | 49.76 mL |
| 1 mM | 2.49 mL | 12.44 mL | 24.88 mL |
| 5 mM | 0.5 mL | 2.49 mL | 4.98 mL |
*The above data is based on the productmolecular weight 401.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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