VE-822

Catalog No. A13289

VE-822是有效的ATR抑制剂。

Technical details

Catalog Num	A13289
M. Wt	463.55
Formula	C24H25N5O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1232416-25-9
Synonyms	VE822, VE 822
SMILES	CC(C)S(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C3=CC(=NO3)C4=CC=C(C=C4)CNC)N

Biological Activity

VE-822是有效的ATR抑制剂。

Targets

ATR (HT29 cells)	ATM (HT29 cells)
19 nM	34 μM

Solubility *

In vitro (25°C)	DMSO	36 mg/mL (77.66 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+45% PEG 300+H2O	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.57 mL	107.86 mL	215.73 mL
0.5 mM	4.31 mL	21.57 mL	43.15 mL
1 mM	2.16 mL	10.79 mL	21.57 mL
5 mM	0.43 mL	2.16 mL	4.31 mL

*The above data is based on the productmolecular weight 463.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.