VER 155008

Catalog No. A13351

VER 155008是HSP70的小分子ATP衍生物抑制剂（IC50 = 500 nM）。

Product Citations

Hiroshi Katoh, .et al. Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation, J Virol, 2017, Mar 15; 91(6): e02220-16 PMID: 28053100

Technical details

Catalog Num	A13351
M. Wt	556.4
Formula	C25H23Cl2N7O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1134156-31-2
Synonyms	VER-155008, VER155008
SMILES	C1=CC(=CC=C1COC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C4=C(C(=NC=N4)N)N=C3NCC5=CC(=C(C=C5)Cl)Cl)O)O)C#N

Biological Activity

VER 155008是HSP70的小分子ATP衍生物抑制剂（IC50 = 500 nM）。

Targets

HSP70	HSC70	GRP78
0.5 μM	2.6 μM	2.6 μM

Solubility *

In vitro	DMSO	Warmed: 93 mg/mL (167.14 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.97 mL	89.86 mL	179.73 mL
0.5 mM	3.59 mL	17.97 mL	35.95 mL
1 mM	1.8 mL	8.99 mL	17.97 mL
5 mM	0.36 mL	1.8 mL	3.59 mL

*The above data is based on the productmolecular weight 556.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.