SAR131675

Catalog No. A13377

SAR131675是一种有效的选择性VEGFR-3-TK抑制剂，具有抗淋巴显形、抗肿瘤和抗转移活性。

Technical details

Catalog Num	A13377
M. Wt	358.29
Formula	C18H22N4O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1433953-83-3
Synonyms	0
SMILES	CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#C[C@](C)(COC)O)C(=O)NC)N

Biological Activity

SAR131675是一种有效的选择性VEGFR-3-TK抑制剂，具有抗淋巴显形、抗肿瘤和抗转移活性。

Targets

VEGFR3 (Cell-free assay)
23 nM

Solubility *

In vitro (25°C)	DMSO	29 mg/mL (80.91 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+5% Tween 80+ddH2O	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.91 mL	139.55 mL	279.1 mL
0.5 mM	5.58 mL	27.91 mL	55.82 mL
1 mM	2.79 mL	13.96 mL	27.91 mL
5 mM	0.56 mL	2.79 mL	5.58 mL

*The above data is based on the productmolecular weight 358.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.