(-)-MK 801 maleate

Catalog No. A13435

(-)-MK 801 maleate是一种有效的、选择性的、非竞争性的NMDA受体拮抗剂。它通过与NMDA相关离子通道内的一个位点结合而起作用。

Technical details

Catalog Num	A13435
M. Wt	337.37
Formula	C16H15NC4H4O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	121917-57-5
Synonyms	MK801, MK-801
SMILES	C[C@]12C3=CC=CC=C3C[C@H](N1)C4=CC=CC=C24.C(=C/C(=O)O)\C(=O)O

Biological Activity

(-)-MK 801 maleate是一种有效的、选择性的、非竞争性的NMDA受体拮抗剂。它通过与NMDA相关离子通道内的一个位点结合而起作用。

Targets

NMDA Receptor
30.5 nM(Ki)

Solubility *

In vitro (25°C)	DMSO	63 mg/mL (186.73 mM)
	Water	Insoluble
	Ethanol	7 mg/mL (20.74 mM)
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	7 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.64 mL	148.21 mL	296.41 mL
0.5 mM	5.93 mL	29.64 mL	59.28 mL
1 mM	2.96 mL	14.82 mL	29.64 mL
5 mM	0.59 mL	2.96 mL	5.93 mL

*The above data is based on the productmolecular weight 337.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.