Napabucasin

Catalog No. A13474

Napabucasin是一种口服小分子药物，它可以阻止癌症干细胞（CSC）自我更新，并诱导CSC和非干细胞中的细胞死亡。

Technical details

Catalog Num	A13474
M. Wt	240.21
Formula	C14H8O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	83280-65-3
Synonyms	BBI 608, BBI608, BBI-608
SMILES	O=C(C1=C2OC(C(C)=O)=C1)C3=C(C2=O)C=CC=C3

Biological Activity

Napabucasin是一种口服小分子药物，它可以阻止癌症干细胞（CSC）自我更新，并诱导CSC和非干细胞中的细胞死亡。

Targets

Stat3

Solubility *

In vitro (25°C)	DMSO	10 mg/mL (41.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+40% PEG 300+5% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	41.63 mL	208.15 mL	416.3 mL
0.5 mM	8.33 mL	41.63 mL	83.26 mL
1 mM	4.16 mL	20.82 mL	41.63 mL
5 mM	0.83 mL	4.16 mL	8.33 mL

*The above data is based on the productmolecular weight 240.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.