Z-FL-COCHO

Catalog No. A13502

Z-FL-COCHO是新型的组织蛋白酶S抑制剂。
  • Fu R, .et al. Cathepsin S activation contributes to elevated CX3CL1 (fractalkine) levels in tears of a Sjogren's syndrome murine model, Sci Rep, 2020, Jan 29;10(1):1455 PMID: 31996771
  • Klinngam W, .et al. Inhibition of Cathepsin S Reduces Lacrimal Gland Inflammation and Increases Tear Flow in a Mouse Model of Sj?gren's Syndrome, Sci Rep, 2019, Jul 2;9(1):9559 PMID: 31267034
  • Chen CY, .et al. Omega-3 polyunsaturated fatty acids reduce preterm labor by inhibiting trophoblast cathepsin S and inflammasome activation, Clin Sci (Lond), 2018, Oct 29;132(20):2221-2239 PMID: 30287519
Catalog Num A13502
M. Wt 442.5
Formula C24H30N2O6
Purity >98%
Storage at -20°C 3 years Powder
CAS No. N/A (Not Available)
Synonyms Cathepsin S inhibitor
SMILES CNC(=O)O[C@H]1COC2=C([C@@H]1NC(=O)C3=CC=C(C=C3)F)C=C(C=C2)N4CCN(CC4)C5COC5
Z-FL-COCHO是新型的组织蛋白酶S抑制剂。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.6 mL 112.99 mL 225.99 mL
0.5 mM 4.52 mL 22.6 mL 45.2 mL
1 mM 2.26 mL 11.3 mL 22.6 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.