AG-1288

Catalog No. A13587

AG-1288是酪氨酸激酶抑制剂。已显示在人羊膜细胞(IC50 = 21 mM)中,可阻断糖皮质激素诱导的细胞毒性,TNFα诱导的细胞毒性和糖皮质激素诱导的COX-2活性。
Catalog Num A13587
M. Wt 231.2
Formula C10H5N3O4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 116313-73-6
Synonyms AG1288, AG 1288, Tyrphostin AG 1288
SMILES C1=C(C=C(C(=C1[N+](=O)[O-])O)O)C=C(C#N)C#N
AG-1288是酪氨酸激酶抑制剂。已显示在人羊膜细胞(IC50 = 21 mM)中,可阻断糖皮质激素诱导的细胞毒性,TNFα诱导的细胞毒性和糖皮质激素诱导的COX-2活性。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 43.25 mL 216.26 mL 432.53 mL
0.5 mM 8.65 mL 43.25 mL 86.51 mL
1 mM 4.33 mL 21.63 mL 43.25 mL
5 mM 0.87 mL 4.33 mL 8.65 mL

*The above data is based on the productmolecular weight 231.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.