BI-78D3

Catalog No. A13683

BI-78D3是一种竞争性JNK(c-Jun N端激酶)抑制剂(IC50 = 280 nM),其选择性是p38α的100倍以上,在mTOR和PI-3K上无活性。 BI 78D3抑制JIP1(JNK相互作用蛋白1)JNK结合(IC50 = 500 nM)。
Catalog Num A13683
M. Wt 379
Formula C13H9N5O5S2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 883065-90-5
Synonyms BI 78D3, BI78D3
SMILES C1COC2=C(O1)C=CC(=C2)N3C(=O)NN=C3SC4=NC=C(S4)[N+](=O)[O-]
BI-78D3是一种竞争性JNK(c-Jun N端激酶)抑制剂(IC50 = 280 nM),其选择性是p38α的100倍以上,在mTOR和PI-3K上无活性。 BI 78D3抑制JIP1(JNK相互作用蛋白1)JNK结合(IC50 = 500 nM)。
Targets
JNK
280 nM
In vitro DMSO 89 mg/mL (234.6 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.39 mL 131.93 mL 263.85 mL
0.5 mM 5.28 mL 26.39 mL 52.77 mL
1 mM 2.64 mL 13.19 mL 26.39 mL
5 mM 0.53 mL 2.64 mL 5.28 mL

*The above data is based on the productmolecular weight 379. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.