Icotinib Hydrochloride
Catalog No. A13718
Icotinib hydrochloride是一种有效的特异性表皮生长因子受体(EGFR)酪氨酸激酶抑制剂(TKI),IC(50)为5 nM,包括EGFR(L858R),EGFR(L861Q),EGFR(T790M)和EGFR的突变体(T790M,L858R)。
Catalog Num | A13718 |
---|---|
M. Wt | 427.88 |
Formula | C22H22ClN3O4 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1204313-51-8 |
Synonyms | BPI-2009H |
SMILES | C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4.Cl |
Icotinib hydrochloride是一种有效的特异性表皮生长因子受体(EGFR)酪氨酸激酶抑制剂(TKI),IC(50)为5 nM,包括EGFR(L858R),EGFR(L861Q),EGFR(T790M)和EGFR的突变体(T790M,L858R)。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.37 mL | 116.86 mL | 233.71 mL |
0.5 mM | 4.67 mL | 23.37 mL | 46.74 mL |
1 mM | 2.34 mL | 11.69 mL | 23.37 mL |
5 mM | 0.47 mL | 2.34 mL | 4.67 mL |
*The above data is based on the productmolecular weight 427.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.