Atorvastatin

Catalog No. A13743

Atorvastatin是一种HMG-CoA还原酶抑制剂（IC50 = 154 nM），可有效治疗高胆固醇血症和某些血脂异常。

Product Citations

Huang Y, .et al. Downregulation of connective tissue growth factor reduces migration and invasiveness of osteosarcoma cells, Mol Med Rep, 2016, Feb;13(2):1888-94 PMID: 26707502

Technical details

Catalog Num	A13743
M. Wt	558.6
Formula	C33H35FN2O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	134523-00-5
Synonyms	Cardyl
SMILES	CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4

Biological Activity

Atorvastatin是一种HMG-CoA还原酶抑制剂（IC50 = 154 nM），可有效治疗高胆固醇血症和某些血脂异常。

Solubility *

In vitro	DMSO	90 mg/mL (161.1 mM)
	Water
	Ethanol
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.9 mL	89.51 mL	179.02 mL
0.5 mM	3.58 mL	17.9 mL	35.8 mL
1 mM	1.79 mL	8.95 mL	17.9 mL
5 mM	0.36 mL	1.79 mL	3.58 mL

*The above data is based on the productmolecular weight 558.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.