Medetomidine HCl

Catalog No. A13775

Medetomidine Hydrochloride是一种肾上腺素α2-受体激动剂，Ki为1.08 nM，比作用于α1-adrenoceptor选择性高1620倍。由于其镇痛和镇静作用而被用于兽医学。

Technical details

Catalog Num	A13775
M. Wt	236.74
Formula	C13H16N2.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	86347-15-1
Synonyms	MonoHydrochloride, Domitor, MPV 785, Metomidine, Zalopine, Detomidine HCl
SMILES	CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl

Biological Activity

Medetomidine Hydrochloride是一种肾上腺素α2-受体激动剂，Ki为1.08 nM，比作用于α1-adrenoceptor选择性高1620倍。由于其镇痛和镇静作用而被用于兽医学。

Targets

α2-adrenoceptor
1.08 nM(Ki)

Solubility *

In vitro (25°C)	DMSO	12 mg/mL (50.68 mM)
	Water	45 mg/mL (190.08 mM)
	Ethanol	45 mg/mL (190.08 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	42.24 mL	211.2 mL	422.4 mL
0.5 mM	8.45 mL	42.24 mL	84.48 mL
1 mM	4.22 mL	21.12 mL	42.24 mL
5 mM	0.84 mL	4.22 mL	8.45 mL

*The above data is based on the productmolecular weight 236.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.