FH535

Catalog No. A13795

FH535是Wnt/β-catenin和PPAR的抑制剂，具有抗肿瘤活性。

Product Citations

Dongdong Fang, etc. Epithelial-Mesenchymal Transition of Ovarian Cancer Cells Is Sustained by Rac1 through Simultaneous Activation of MEK1/2 and Src Signaling Pathways. Oncogene. 2017 Mar; 36(11): 1546–1558.

Technical details

Catalog Num	A13795
M. Wt	361.2
Formula	C13H10Cl2N2O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	108409-83-2
Synonyms	FH-535, FH 535
SMILES	CC1=C(C=CC(=C1)[N+](=O)[O-])NS(=O)(=O)C2=C(C=CC(=C2)Cl)Cl

Biological Activity

FH535是Wnt/β-catenin和PPAR的抑制剂，具有抗肿瘤活性。

Targets

Wnt/β-catenin	PPARγ	PPARδ

Solubility *

In vitro	DMSO	Warmed: 61 mg/mL (168.88 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.69 mL	138.43 mL	276.85 mL
0.5 mM	5.54 mL	27.69 mL	55.37 mL
1 mM	2.77 mL	13.84 mL	27.69 mL
5 mM	0.55 mL	2.77 mL	5.54 mL

*The above data is based on the productmolecular weight 361.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.