JIB-04
Catalog No. A13806
JIB-04是一种全选择性Jumonji组蛋白脱甲基酶抑制剂，对于JARID1A，JMJD2E，JMJD3，JMJD2A，JMJD2B，JMJD2C和JMJD2D，IC50分别为230、340、855、445、435、1100和290 nM。
| Catalog Num | A13806 |
|---|---|
| M. Wt | 308.76 |
| Formula | C17H13ClN4 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 199596-05-9 |
| Synonyms | NSC 693627, JIB04 |
| SMILES | C1=CC=C(C=C1)/C(=N\NC2=NC=C(C=C2)Cl)/C3=CC=CC=N3 |
JIB-04是一种全选择性Jumonji组蛋白脱甲基酶抑制剂，对于JARID1A，JMJD2E，JMJD3，JMJD2A，JMJD2B，JMJD2C和JMJD2D，IC50分别为230、340、855、445、435、1100和290 nM。
| In vitro (25°C) | DMSO | Warmed: 22 mg/mL (71.24 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 4% DMSO+corn oil | 2 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.39 mL | 161.94 mL | 323.88 mL |
| 0.5 mM | 6.48 mL | 32.39 mL | 64.78 mL |
| 1 mM | 3.24 mL | 16.19 mL | 32.39 mL |
| 5 mM | 0.65 mL | 3.24 mL | 6.48 mL |
*The above data is based on the productmolecular weight 308.76. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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