FLI-06

Catalog No. A13815

FLI-06是一种Notch抑制剂和早期分泌途径抑制剂。FLI-06以不同于布雷菲德菌素A和杀真菌剂A的方式破坏高尔基体。

Product Citations

Tan YJ, .et al. Anticancer activities of a benzimidazole compound through sirtuin inhibition in colorectal cancer, Future Med Chem, 2018, Sep 1;10(17):2039-2057 PMID: 30066578

Technical details

Catalog Num	A13815
M. Wt	438.52
Formula	C25H30N2O5
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	313967-18-9
Synonyms	FLI06,FLI 06
SMILES	CC1=C(C(C2=C(N1)CC(CC2=O)(C)C)C3=CC=C(C=C3)[N+](=O)[O-])C(=O)OC4CCCCC4

Biological Activity

FLI-06是一种Notch抑制剂和早期分泌途径抑制剂。FLI-06以不同于布雷菲德菌素A和杀真菌剂A的方式破坏高尔基体。

Targets

Notch
2.3 μM(EC50)

Solubility *

In vitro	DMSO	80 mg/mL (182.43 mM)
	Water	Insoluble
	Ethanol	7 mg/mL (15.96 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.8 mL	114.02 mL	228.04 mL
0.5 mM	4.56 mL	22.8 mL	45.61 mL
1 mM	2.28 mL	11.4 mL	22.8 mL
5 mM	0.46 mL	2.28 mL	4.56 mL

*The above data is based on the productmolecular weight 438.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.