D4476

Catalog No. A13949

D4476是酪蛋白激酶1的细胞渗透抑制剂。

Technical details

Catalog Num	A13949
M. Wt	398.41
Formula	C23H18N4O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	301836-43-1
Synonyms	D 4476, D-4476
SMILES	C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5

Biological Activity

D4476是酪蛋白激酶1的细胞渗透抑制剂。

Targets

CK1 from Schizosaccharomyces pombe	CK1δ	ALK5
200 nM	300 nM	500 nM

Solubility *

In vitro	DMSO	71 mg/mL (178.2 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.1 mL	125.5 mL	251 mL
0.5 mM	5.02 mL	25.1 mL	50.2 mL
1 mM	2.51 mL	12.55 mL	25.1 mL
5 mM	0.5 mL	2.51 mL	5.02 mL

*The above data is based on the productmolecular weight 398.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.