GNE0877

Catalog No. A13969

GNE-0877是一种高效且选择性的LRRK2抑制剂。

Technical details

Catalog Num	A13969
M. Wt	339.31895
Formula	C14H16F3N7
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1374828-69-9
Synonyms	GNE-0877, GNE 0877, GNE0877
SMILES	CC1=NN(C=C1NC2=NC=C(C(=N2)NC)C(F)(F)F)C(C)(C)C#N

Biological Activity

GNE-0877是一种高效且选择性的LRRK2抑制剂。

Targets

LRRK2
0.7 nM(Ki)

Solubility *

In vitro	DMSO	63 mg/mL (185.66 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.47 mL	147.35 mL	294.71 mL
0.5 mM	5.89 mL	29.47 mL	58.94 mL
1 mM	2.95 mL	14.74 mL	29.47 mL
5 mM	0.59 mL	2.95 mL	5.89 mL

*The above data is based on the productmolecular weight 339.31895. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.