NSC-23766 HClCatalog No. A13975

Quick Overview

NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 uM).
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NSC-23766 HCl

Product Information
Catalog Num A13975
M. Wt 531
Formula C24H35N7.3HCl
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 1177865-17-6
Synonyms NSC 23766, NSC23766
Chemical Name N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine,? trihydrochloride
SMILES Code CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C2)N=C(C=C3N)C)C.Cl.Cl.Cl

Biological activity
Introduction
NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs TrioN and Tiam 1 (IC50 = 50 uM).
Targets
Rac GTPase (Cell-free assay)
50 μM
Solubility
Solubility (25C)* In vitro DMSO 100 mg/mL heating (188.33 mM)
Water 100 mg/mL heating (188.33 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Return Policy Contact information
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High Purity Kinase Inhibitors on Signaling Pathways

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