GNE-317

Catalog No. A13992

GNE-317是一种有效的PI3K抑制剂，可以穿过血液的脑屏障。显示了完整BBB小鼠大脑中PI3K途径的有效抑制。

Technical details

Catalog Num	A13992
M. Wt	414.48
Formula	C19H22N6O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1394076-92-6
Synonyms	GNE317, GNE 317
SMILES	COC1(COC1)C2=C(C)C3=C(S2)C(N4CCOCC4)=NC(C5=CN=C(N)N=C5)=N3

Biological Activity

GNE-317是一种有效的PI3K抑制剂，可以穿过血液的脑屏障。显示了完整BBB小鼠大脑中PI3K途径的有效抑制。

Targets

PI3K

Solubility *

In vitro	DMSO	Warmed: 40 mg/mL (96.5 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.13 mL	120.63 mL	241.27 mL
0.5 mM	4.83 mL	24.13 mL	48.25 mL
1 mM	2.41 mL	12.06 mL	24.13 mL
5 mM	0.48 mL	2.41 mL	4.83 mL

*The above data is based on the productmolecular weight 414.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.