TTP-22

Catalog No. A14101

TTP 22是一种高亲和力的酪蛋白激酶2(CK2)抑制剂(IC50 = 0.1uM,Ki = 40nM)。另外,TTP 22显示出对CK2的选择性超过JNK3,ROCK1和MET(显示出的抑制作用大于10 uM)。TTP 22是高度保守的丝氨酸/苏氨酸蛋白激酶,也参与细胞增殖,细胞分化和凋亡。
Catalog Num A14101
M. Wt 330.42
Formula C16H14N2O2S2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 329907-28-0
Synonyms TTP 22, TTP22
SMILES CC1=CC=C(C=C1)C2=CSC3=C2C(=NC=N3)SCCC(=O)O
TTP 22是一种高亲和力的酪蛋白激酶2(CK2)抑制剂(IC50 = 0.1uM,Ki = 40nM)。另外,TTP 22显示出对CK2的选择性超过JNK3,ROCK1和MET(显示出的抑制作用大于10 uM)。TTP 22是高度保守的丝氨酸/苏氨酸蛋白激酶,也参与细胞增殖,细胞分化和凋亡。
In vitro DMSO 63 mg/mL (190.66 mM)
Water Insoluble
Ethanol 8 mg/mL (24.21 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.26 mL 151.32 mL 302.65 mL
0.5 mM 6.05 mL 30.26 mL 60.53 mL
1 mM 3.03 mL 15.13 mL 30.26 mL
5 mM 0.61 mL 3.03 mL 6.05 mL

*The above data is based on the productmolecular weight 330.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.