B-Raf-inhibitor 1

Catalog No. A14122

B-Raf inhibitor 1是有效的选择性B-Raf抑制剂,对A375增殖和A375 p-ERK的细胞IC50分别为0.31 uM和2 nM。
Catalog Num A14122
M. Wt 478.94
Formula C26H19ClN8
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1093100-40-3
Synonyms B-Raf inhibitor1, B-Raf inhibitor-1
SMILES CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6
B-Raf inhibitor 1是有效的选择性B-Raf抑制剂,对A375增殖和A375 p-ERK的细胞IC50分别为0.31 uM和2 nM。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.88 mL 104.4 mL 208.79 mL
0.5 mM 4.18 mL 20.88 mL 41.76 mL
1 mM 2.09 mL 10.44 mL 20.88 mL
5 mM 0.42 mL 2.09 mL 4.18 mL

*The above data is based on the productmolecular weight 478.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.