TMP 269

Catalog No. A14128

TMP 269是一种有效的选择性IIa类HDAC抑制剂,对HDAC4,HDAC5,HDAC7和HDAC9的IC50分别为157 nM,97 nM,43 nM和23 nM。
Catalog Num A14128
M. Wt 514.52
Formula C25H21F3N4O3S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1314890-29-3
Synonyms TMP-269,TMP269
SMILES O=C(c1cccc(c1)c1noc(n1)C(F)(F)F)NCC1(CCOCC1)c1scc(n1)c1ccccc1
TMP 269是一种有效的选择性IIa类HDAC抑制剂,对HDAC4,HDAC5,HDAC7和HDAC9的IC50分别为157 nM,97 nM,43 nM和23 nM。
In vitro DMSO 89 mg/mL (172.97 mM)
Water Insoluble
Ethanol Warmed: 2 mg/mL (3.88 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.44 mL 97.18 mL 194.36 mL
0.5 mM 3.89 mL 19.44 mL 38.87 mL
1 mM 1.94 mL 9.72 mL 19.44 mL
5 mM 0.39 mL 1.94 mL 3.89 mL

*The above data is based on the productmolecular weight 514.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.