Miltefosine

Catalog No. A14138

Miltefosine在癌细胞系A431和HeLa中抑制PI3K/Akt活性，ED50为17.2μM和8.1μM。

Technical details

Catalog Num	A14138
M. Wt	407.6
Formula	C21H46NO4P
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	58066-85-6
Synonyms	HePC
SMILES	CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C

Biological Activity

Miltefosine在癌细胞系A431和HeLa中抑制PI3K/Akt活性，ED50为17.2μM和8.1μM。

Targets

Akt	PI3K	PKC
N/A		~7 μM

Solubility *

In vitro (25°C)	DMSO	Insoluble
	Water	77 mg/mL (188.92 mM)
	Ethanol	77 mg/mL (188.92 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.53 mL	122.67 mL	245.34 mL
0.5 mM	4.91 mL	24.53 mL	49.07 mL
1 mM	2.45 mL	12.27 mL	24.53 mL
5 mM	0.49 mL	2.45 mL	4.91 mL

*The above data is based on the productmolecular weight 407.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.