4EGI-1

Catalog No. A14199

4EGI-1是一种竞争性eIF4E/eIF4G相互作用抑制剂，KD值 25 uM。

Technical details

Catalog Num	A14199
M. Wt	451.28
Formula	C18H12Cl2N4O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	315706-13-9
Synonyms	4EGI1, 4EGI 1
SMILES	C1=CC=C(C(=C1)CC(=NNC2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)C(=O)O)[N+](=O)[O-]

Biological Activity

4EGI-1是一种竞争性eIF4E/eIF4G相互作用抑制剂，KD值 25 uM。

Targets

eIF4E/eIF4G
25 μM(Kd)

Solubility *

In vitro (25°C)	DMSO	79 mg/mL (175.06 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+pbs	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.16 mL	110.8 mL	221.59 mL
0.5 mM	4.43 mL	22.16 mL	44.32 mL
1 mM	2.22 mL	11.08 mL	22.16 mL
5 mM	0.44 mL	2.22 mL	4.43 mL

*The above data is based on the productmolecular weight 451.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.