Splitomicin

Catalog No. A14221

Splitomicin是一种选择性的NAD(+)-依赖性组蛋白脱乙酰基酶Sir2p抑制剂，IC50为60 uM，在基于细胞的测定中显示出更高的活性。

Technical details

Catalog Num	A14221
M. Wt	198.22
Formula	C13H10O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	CAS: 5690-03-9
Synonyms
SMILES	C1CC(=O)OC2=C1C3=CC=CC=C3C=C2

Biological Activity

Splitomicin是一种选择性的NAD(+)-依赖性组蛋白脱乙酰基酶Sir2p抑制剂，IC50为60 uM，在基于细胞的测定中显示出更高的活性。

Targets

Sir2p
60 μM

Solubility *

In vitro	DMSO	37 mg/mL (186.66 mM)
	Water	Insoluble
	Ethanol	37 mg/mL (186.66 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	50.45 mL	252.24 mL	504.49 mL
0.5 mM	10.09 mL	50.45 mL	100.9 mL
1 mM	5.04 mL	25.22 mL	50.45 mL
5 mM	1.01 mL	5.04 mL	10.09 mL

*The above data is based on the productmolecular weight 198.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.