AGK2

Catalog No. A14225

AGK2是一种有效的选择性SIRT2抑制剂，IC50为3.5μM。

Technical details

Catalog Num	A14225
M. Wt	434.27
Formula	C23H13Cl2N3O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	304896-28-4
Synonyms	AGK 2
SMILES	C1=CC2=C(C=CC=N2)C(=C1)NC(=O)/C(=C/C3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)/C#N

Biological Activity

AGK2是一种有效的选择性SIRT2抑制剂，IC50为3.5μM。

Targets

SIRT2
3.5 μM

Solubility *

In vitro (25°C)	DMSO	Warmed: 10 mg/mL (23.02 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	8% DMSO+30% PEG 300+ddH2O	1.3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.03 mL	115.14 mL	230.27 mL
0.5 mM	4.61 mL	23.03 mL	46.05 mL
1 mM	2.3 mL	11.51 mL	23.03 mL
5 mM	0.46 mL	2.3 mL	4.61 mL

*The above data is based on the productmolecular weight 434.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.