ESI-09

Catalog No. A14233

ESI-09是一种直接由cAMP（EPAC）抑制剂激活的特异性交换蛋白，对于EPAC1和EPAC2，IC50为3.2 uM和1.4 uM。

Technical details

Catalog Num	A14233
M. Wt	330.77
Formula	C16H15ClN4O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	263707-16-0
Synonyms	0
SMILES	CC(C)(C)C1=CC(=NO1)C(=O)/C(=N/NC2=CC(=CC=C2)Cl)/C#N

Biological Activity

ESI-09是一种直接由cAMP（EPAC）抑制剂激活的特异性交换蛋白，对于EPAC1和EPAC2，IC50为3.2 uM和1.4 uM。

Targets

EPAC2	EPAC1
1.4 μM	3.2 μM

Solubility *

In vitro (25°C)	DMSO	63 mg/mL (190.46 mM)
	Water	Insoluble
	Ethanol	Warmed: 19 mg/mL (57.44 mM)
In vivo	10% ethanol+10% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.23 mL	151.16 mL	302.32 mL
0.5 mM	6.05 mL	30.23 mL	60.46 mL
1 mM	3.02 mL	15.12 mL	30.23 mL
5 mM	0.6 mL	3.02 mL	6.05 mL

*The above data is based on the productmolecular weight 330.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.