ARQ 621

Catalog No. A14234

ARQ 621是一种变构选择性Eg5有丝分裂运动蛋白抑制剂。

Technical details

Catalog Num	A14234
M. Wt	552.43
Formula	C28H24Cl2FN5O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1095253-39-6
Synonyms	0
SMILES	C#CC[C@H](C1=NC2=C(C=CC(=C2)Cl)C(=O)N1NC3=CC=CC=C3)N(CCCN)C(=O)C4=C(C(=CC=C4)Cl)F

Biological Activity

ARQ 621是一种变构选择性Eg5有丝分裂运动蛋白抑制剂。

Targets

Eg5 mitotic motor protein

Solubility *

In vitro	DMSO	89 mg/mL (161.1 mM)
	Water	Insoluble
	Ethanol	89 mg/mL (161.1 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.1 mL	90.51 mL	181.02 mL
0.5 mM	3.62 mL	18.1 mL	36.2 mL
1 mM	1.81 mL	9.05 mL	18.1 mL
5 mM	0.36 mL	1.81 mL	3.62 mL

*The above data is based on the productmolecular weight 552.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.