Santacruzamate A

Catalog No. A14236

Santacruzamate A (CAY10683)是一种有效的选择性HDAC抑制剂，对HDAC2的IC50为119 pM，选择性是其他HDAC的3600倍以上。

Technical details

Catalog Num	A14236
M. Wt	278.35
Formula	C15H22N2O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1477949-42-0
Synonyms	CAY10683
SMILES	CCOC(=O)NCCCC(=O)NCCC1=CC=CC=C1

Biological Activity

Santacruzamate A (CAY10683)是一种有效的选择性HDAC抑制剂，对HDAC2的IC50为119 pM，选择性是其他HDAC的3600倍以上。

Targets

HDAC2	HDAC6	HDAC4
119 pM	434 nM	>1000 nM

Solubility *

In vitro (25°C)	DMSO	47 mg/mL (168.85 mM)
	Water	Insoluble
	Ethanol	47 mg/mL (168.85 mM)
In vivo	5%DMSO+30%PEG300+5%TW80+H2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35.93 mL	179.63 mL	359.26 mL
0.5 mM	7.19 mL	35.93 mL	71.85 mL
1 mM	3.59 mL	17.96 mL	35.93 mL
5 mM	0.72 mL	3.59 mL	7.19 mL

*The above data is based on the productmolecular weight 278.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.