Labetalol HCl

Catalog No. A14239

Labetalol HCl是选择性α1-肾上腺素能受体和非选择性β-肾上腺素能受体的双重拮抗剂。

Product Citations

Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Technical details

Catalog Num	A14239
M. Wt	364.87
Formula	C19H25ClN2O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	32780-64-6
Synonyms	0
SMILES	CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl

Biological Activity

Labetalol HCl是选择性α1-肾上腺素能受体和非选择性β-肾上腺素能受体的双重拮抗剂。

Targets

α1-adrenergic receptor	β-adrenergic receptor

Solubility *

In vitro	DMSO	63 mg/mL (172.66 mM)
	Water	7 mg/mL (19.18 mM)
	Ethanol	6 mg/mL (16.44 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.41 mL	137.04 mL	274.07 mL
0.5 mM	5.48 mL	27.41 mL	54.81 mL
1 mM	2.74 mL	13.7 mL	27.41 mL
5 mM	0.55 mL	2.74 mL	5.48 mL

*The above data is based on the productmolecular weight 364.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.