SH-4-54

Catalog No. A14249

SH-4-54是一种有效的STAT抑制剂,对STAT3和STAT5的KD为300 nM和464 nM。
Catalog Num A14249
M. Wt 610.59
Formula C29H27F5N2O5S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1456632-40-8
Synonyms SH454
SMILES CN(CC(=O)N(CC1=CC=C(C=C1)C2CCCCC2)C3=CC=C(C=C3)C(=O)O)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F
SH-4-54是一种有效的STAT抑制剂,对STAT3和STAT5的KD为300 nM和464 nM。
Targets
STAT3 STAT5
300 nM(Kd)464 nM(Kd)
In vitro DMSO 94 mg/mL (153.94 mM)
Water Insoluble
Ethanol Warmed: 47 mg/mL (76.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.38 mL 81.89 mL 163.78 mL
0.5 mM 3.28 mL 16.38 mL 32.76 mL
1 mM 1.64 mL 8.19 mL 16.38 mL
5 mM 0.33 mL 1.64 mL 3.28 mL

*The above data is based on the productmolecular weight 610.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.