Darapladib

Catalog No. A14274

Darapladib是一种可逆的脂蛋白相关磷脂酶A2（Lp-PLA2）抑制剂。

Technical details

Catalog Num	A14274
M. Wt	666.77
Formula	C36H38F4N4O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	356057-34-6
Synonyms	SB-480848
SMILES	CCN(CC)CCN(CC1=CC=C(C=C1)C2=CC=C(C=C2)C(F)(F)F)C(=O)CN3C4=C(CCC4)C(=O)N=C3SCC5=CC=C(C=C5)F

Biological Activity

Darapladib是一种可逆的脂蛋白相关磷脂酶A2（Lp-PLA2）抑制剂。

Targets

Lp-PLA2
0.25 nM

Solubility *

In vitro	DMSO	Warmed: 96 mg/mL (143.97 mM)
	Water	Insoluble
	Ethanol	96 mg/mL (143.97 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15 mL	74.99 mL	149.98 mL
0.5 mM	3 mL	15 mL	30 mL
1 mM	1.5 mL	7.5 mL	15 mL
5 mM	0.3 mL	1.5 mL	3 mL

*The above data is based on the productmolecular weight 666.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.