Triapine

Catalog No. A14306

Triapine是一种有效的核糖核苷酸还原酶抑制剂，具有抑制DNA合成的广谱抗肿瘤活性。

Technical details

Catalog Num	A14306
M. Wt	195.24
Formula	C7H9N5S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	200933-27-3
Synonyms	3-AP
SMILES	C1=CC(=C(N=C1)C=NNC(=S)N)N

Biological Activity

Triapine是一种有效的核糖核苷酸还原酶抑制剂，具有抑制DNA合成的广谱抗肿瘤活性。

Targets

Ribonucleotide reductase

Solubility *

In vitro (25°C)	DMSO	17 mg/mL (87.07 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	1.18 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	51.22 mL	256.1 mL	512.19 mL
0.5 mM	10.24 mL	51.22 mL	102.44 mL
1 mM	5.12 mL	25.61 mL	51.22 mL
5 mM	1.02 mL	5.12 mL	10.24 mL

*The above data is based on the productmolecular weight 195.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.