ME0328

Catalog No. A14309

ME0328是一种有效的选择性PARP抑制剂，对PARP3的IC50为0.89μM，选择性是PARP1的7倍。

Technical details

Catalog Num	A14309
M. Wt	321.37
Formula	C19H19N3O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1445251-22-8
Synonyms	ME 0328
SMILES	C[C@@H](C1=CC=CC=C1)NC(=O)CCC2=NC(=O)C3=CC=CC=C3N2

Biological Activity

ME0328是一种有效的选择性PARP抑制剂，对PARP3的IC50为0.89μM，选择性是PARP1的7倍。

Targets

PARP3	PARP1
0.89 μM	6.3 μM

Solubility *

In vitro	DMSO	60 mg/mL (186.69 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.12 mL	155.58 mL	311.17 mL
0.5 mM	6.22 mL	31.12 mL	62.23 mL
1 mM	3.11 mL	15.56 mL	31.12 mL
5 mM	0.62 mL	3.11 mL	6.22 mL

*The above data is based on the productmolecular weight 321.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.