UNC0379

Catalog No. A14320

UNC0379是赖氨酸甲基转移酶SETD8的选择性底物竞争性抑制剂。它对SETD8的亲和力已通过ITC（等温滴定热量法）和SPR（表面等离振子共振）研究得到证实。

Technical details

Catalog Num	A14320
M. Wt	413.28
Formula	C23H35N5O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1620401-82-2
Synonyms	UNC-0379, UNC 0379
SMILES	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCCC3)NCCCCCN4CCCC4)OC

Biological Activity

UNC0379是赖氨酸甲基转移酶SETD8的选择性底物竞争性抑制剂。它对SETD8的亲和力已通过ITC（等温滴定热量法）和SPR（表面等离振子共振）研究得到证实。

Targets

SETD8
7.9 μM

Solubility *

In vitro	DMSO	79 mg/mL (191.02 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.2 mL	120.98 mL	241.97 mL
0.5 mM	4.84 mL	24.2 mL	48.39 mL
1 mM	2.42 mL	12.1 mL	24.2 mL
5 mM	0.48 mL	2.42 mL	4.84 mL

*The above data is based on the productmolecular weight 413.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.