NLG919

Catalog No. A14322

NLG919是一种吲哚胺2，3-二加氧酶1（IDO1）的口服抑制剂，具有潜在的免疫调节和抗肿瘤活性。

Technical details

Catalog Num	A14322
M. Wt	282.38
Formula	C18H22N2O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1402836-58-1
Synonyms	NLG 919, NLG-919
SMILES	C1CCC(CC1)C(CC2C3=CC=CC=C3C4=CN=CN24)O

Biological Activity

NLG919是一种吲哚胺2，3-二加氧酶1（IDO1）的口服抑制剂，具有潜在的免疫调节和抗肿瘤活性。

Targets

IDO (Cell-free assay)	IDO (Cell-free assay)
75 nM(EC50)	75 nM(EC50)

Solubility *

In vitro	DMSO	Warmed: 13 mg/mL (46.03 mM)
	Water	Insoluble
	Ethanol	26 mg/mL (92.07 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	35.41 mL	177.07 mL	354.13 mL
0.5 mM	7.08 mL	35.41 mL	70.83 mL
1 mM	3.54 mL	17.71 mL	35.41 mL
5 mM	0.71 mL	3.54 mL	7.08 mL

*The above data is based on the productmolecular weight 282.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.