AG-120 (Ivosidenib)

Catalog No. A14386

AG-120 (Ivosidenib)是1型异柠檬酸脱氢酶(IDH1)的口服抑制剂,具有潜在的抗肿瘤活性。
Catalog Num A14386
M. Wt 582.97
Formula C28H22ClF3N6O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1448346-63-1
Synonyms AG120, AG 120, Ivosidenib
SMILES C1CC(=O)N(C1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N
AG-120 (Ivosidenib)是1型异柠檬酸脱氢酶(IDH1)的口服抑制剂,具有潜在的抗肿瘤活性。
In vitro DMSO 95 mg/mL (162.95 mM)
Water Insoluble
Ethanol 95 mg/mL (162.95 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.15 mL 85.77 mL 171.54 mL
0.5 mM 3.43 mL 17.15 mL 34.31 mL
1 mM 1.72 mL 8.58 mL 17.15 mL
5 mM 0.34 mL 1.72 mL 3.43 mL

*The above data is based on the productmolecular weight 582.97. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.