KNK437
Catalog No. A14389
KNK437剂量依赖性地抑制了COLO 320DM(人类结肠癌)细胞中耐热性的获得以及各种HSP的诱导,包括HSP105,HSP70和HSP40。
Catalog Num | A14389 |
---|---|
M. Wt | 245.23 |
Formula | C13H11NO4 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 218924-25-5 |
Synonyms | KNK-437, KNK 437 |
SMILES | O=CN1C(/C(CC1)=C\C2=CC=C(OCO3)C3=C2)=O |
KNK437剂量依赖性地抑制了COLO 320DM(人类结肠癌)细胞中耐热性的获得以及各种HSP的诱导,包括HSP105,HSP70和HSP40。
Targets
HSP105 | HSP72 | HSP40 | ||
In vitro (25°C) | DMSO | Warmed: 14 mg/mL (57.08 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+corn oil | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 40.78 mL | 203.89 mL | 407.78 mL |
0.5 mM | 8.16 mL | 40.78 mL | 81.56 mL |
1 mM | 4.08 mL | 20.39 mL | 40.78 mL |
5 mM | 0.82 mL | 4.08 mL | 8.16 mL |
*The above data is based on the productmolecular weight 245.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.