KNK437

Catalog No. A14389

KNK437剂量依赖性地抑制了COLO 320DM(人类结肠癌)细胞中耐热性的获得以及各种HSP的诱导,包括HSP105,HSP70和HSP40。
Catalog Num A14389
M. Wt 245.23
Formula C13H11NO4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 218924-25-5
Synonyms KNK-437, KNK 437
SMILES O=CN1C(/C(CC1)=C\C2=CC=C(OCO3)C3=C2)=O
KNK437剂量依赖性地抑制了COLO 320DM(人类结肠癌)细胞中耐热性的获得以及各种HSP的诱导,包括HSP105,HSP70和HSP40。
Targets
HSP105 HSP72 HSP40
In vitro (25°C) DMSO Warmed: 14 mg/mL (57.08 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.78 mL 203.89 mL 407.78 mL
0.5 mM 8.16 mL 40.78 mL 81.56 mL
1 mM 4.08 mL 20.39 mL 40.78 mL
5 mM 0.82 mL 4.08 mL 8.16 mL

*The above data is based on the productmolecular weight 245.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.