Solcitinib (GSK2586184)

Catalog No. A14405

Solcitinib (GSK2586184)是Janus激酶1（JAK1）抑制剂。

Technical details

Catalog Num	A14405
M. Wt	389.45
Formula	C22H23N5O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1206163-45-2
Synonyms	GSK2586184, GSK 2586184, GSK-2586184, GLPG0778, GLPG 0778, GLPG-0778, G154578
SMILES	CC1(CN(C1)C(=O)C2=CC=C(C=C2)C3=CC=CC4=NC(=NN43)NC(=O)C5CC5)C

Biological Activity

Solcitinib (GSK2586184)是Janus激酶1（JAK1）抑制剂。

Solubility *

In vitro	DMSO	27 mg/mL (69.33 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (7.7 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.68 mL	128.39 mL	256.77 mL
0.5 mM	5.14 mL	25.68 mL	51.35 mL
1 mM	2.57 mL	12.84 mL	25.68 mL
5 mM	0.51 mL	2.57 mL	5.14 mL

*The above data is based on the productmolecular weight 389.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Solcitinib (GSK2586184)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions