Debio-1347 (CH5183284)

Catalog No. A14415

Debio-1347 (CH5183284)是成纤维细胞生长因子受体亚型1(FGFR-1),2(FGFR-2)和3(FGFR-3)的生物利用抑制剂,具有潜在的抗肿瘤活性。
Catalog Num A14415
M. Wt 356.38
Formula C20H16N6O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1265229-25-1
Synonyms Debio 1347, Debio1347, CH5183284, CH 5183284, CH-5183284, FF-284, FF284, FF 284
SMILES CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N
Debio-1347 (CH5183284)是成纤维细胞生长因子受体亚型1(FGFR-1),2(FGFR-2)和3(FGFR-3)的生物利用抑制剂,具有潜在的抗肿瘤活性。
Targets
FGFR2 FGFR1 FGFR3 FGFR4
7.6 nM9.3 nM22 nM290 nM
In vitro DMSO 70 mg/mL (196.41 mM)
Water Insoluble
Ethanol Warmed: 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.06 mL 140.3 mL 280.6 mL
0.5 mM 5.61 mL 28.06 mL 56.12 mL
1 mM 2.81 mL 14.03 mL 28.06 mL
5 mM 0.56 mL 2.81 mL 5.61 mL

*The above data is based on the productmolecular weight 356.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.