RTA-408
Catalog No. A14417
RTA-408是一种合成的三萜类化合物,可有效激活抗氧化转录因子Nrf2并抑制促炎转录因子NF-kB。
Catalog Num | A14417 |
---|---|
M. Wt | 554.71 |
Formula | C33H44F2N2O3 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1474034-05-3 |
Synonyms | RTA 408, RTA408 |
SMILES | C[C@@]12CC[C@]3(CCC(C[C@H]3[C@H]1C(=O)C=C4[C@]2(CC[C@@H]5[C@@]4(C=C(C(=O)C5(C)C)C#N)C)C)(C)C)NC(=O)C(C)(F)F |
RTA-408是一种合成的三萜类化合物,可有效激活抗氧化转录因子Nrf2并抑制促炎转录因子NF-kB。
Targets
Nrf2 | ||||
In vitro (25°C) | DMSO | 98 mg/mL (176.66 mM) | |
Water | Insoluble | ||
Ethanol | 20 mg/mL (36.05 mM) | ||
In vivo | 10%DMSO+90% Corn oil | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 18.03 mL | 90.14 mL | 180.27 mL |
0.5 mM | 3.61 mL | 18.03 mL | 36.05 mL |
1 mM | 1.8 mL | 9.01 mL | 18.03 mL |
5 mM | 0.36 mL | 1.8 mL | 3.61 mL |
*The above data is based on the productmolecular weight 554.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.