SBE 13 HCl

Catalog No. A14426

SBE 13 HCl是PLK1的选择性抑制剂,对于PLK1,PLK3和PLK2,IC 50值分别为200pM,875nM和66μM。
Catalog Num A14426
M. Wt 479.4
Formula C24H27ClN2O4.HC
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1052532-15-6
Synonyms SBE-13, SBE 13
SMILES COC1=C(C=C(C=C1)CCNCC2=CC(=C(C=C2)OCC3=CN=C(C=C3)Cl)OC)OC.Cl
SBE 13 HCl是PLK1的选择性抑制剂,对于PLK1,PLK3和PLK2,IC 50值分别为200pM,875nM和66μM。
Targets
PLK1 PLK3 PLK2
200 pM875 nM>66 μM
In vitro DMSO 90 mg/mL (187.73 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.86 mL 104.3 mL 208.59 mL
0.5 mM 4.17 mL 20.86 mL 41.72 mL
1 mM 2.09 mL 10.43 mL 20.86 mL
5 mM 0.42 mL 2.09 mL 4.17 mL

*The above data is based on the productmolecular weight 479.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.