ACTB-1003

Catalog No. A14431

ACTB-1003是一种口服激酶抑制剂,靶向癌症突变(FGFR抑制),血管生成(抑制VEGFR2和Tie-2)并诱导凋亡(靶向PI3激酶下游的RSK和p70S6K。
Catalog Num A14431
M. Wt 591.53
Formula C27H26F5N7O3
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 939805-30-8
Synonyms ACTB1003, ACTB 1003
SMILES COCC1=C(N2C(=C1C3=CC(=C(C=C3)NC(=O)NC4=C(C=CC(=C4)C(F)(F)F)F)F)C(=NC=N2)N)CN5CCOCC5
ACTB-1003是一种口服激酶抑制剂,靶向癌症突变(FGFR抑制),血管生成(抑制VEGFR2和Tie-2)并诱导凋亡(靶向PI3激酶下游的RSK和p70S6K。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.91 mL 84.53 mL 169.05 mL
0.5 mM 3.38 mL 16.91 mL 33.81 mL
1 mM 1.69 mL 8.45 mL 16.91 mL
5 mM 0.34 mL 1.69 mL 3.38 mL

*The above data is based on the productmolecular weight 591.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.